Sam Mikhail, MD

Oncology and Hematology
Sam Mikhail, MD

Dr. Mikhail joined the Zangmeister Cancer Center in September 2016. He was most recently a medical oncologist and faculty member at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

Dr. Mikhail has authored numerous articles in medical oncology and hematology. Additionally, he has served as a peer reviewer for multiple medical journals and was selected as an editorial board member for the prestigious journal Nature Scientific Reports. Dr. Mikhail was also selected to be a reviewer for the ASCO University board review questions.

Dr. Mikhail completed his internship and residency at Rochester General Hospital in Rochester, New York, where he was subsequently selected as chief resident. He went on to complete his fellowship and was selected as chief fellow in the Division of Hematology and Oncology at the Georgetown University’s Lombardi Comprehensive Cancer Center in Washington, D.C.

He has mentored multiple trainees who currently are pursuing successful careers in hematology and medical oncology. He also has an interest in cancer support groups and promoting education and awareness about cancer and its prevention. He was recognized by a major insurance company for his high-quality and cost-effective patient care. Dr. Mikhail is actively engaged in research that focuses on improving patient outcomes and using targeted therapies and genomic medicine. He continues to maintain his interest in clinical research at the Zangmeister Cancer Center.

Dr. Mikhail is Board-certified in hematology and medical oncology. He evaluates and treats all blood and cancer disorders with a special interest in gastrointestinal cancers. He is a member of the American Society of Clinical Oncology, American Association for Cancer Research, and International Society of Gastrointestinal Oncology, as well as Community Oncology Alliance, Ohio State Medical Association and Ohio Hematology Oncology Society.

Dr. Mikhail enjoys bike riding and kayaking. He lives in Upper Arlington, Ohio, with his wife and three children.

Jun 27th, 2025
★★★★★
Dr. Mikhail is professional and knowledgeable in responding to my inquiries about the sympotoms and root causes. His interpretations, which are transparent, logical, and comprehensive, have provided me with valuable insights. I have gained a better understanding of how to identify issues, analyze correlations on multiple factors, and take actions to focus on resolving the known problems. I appreciate his dedication, patience, and devotion to saving people's health, for which he has earned my respect.
Review from Google
Jun 20th, 2025
★★★★★
They were very professional, and thorough they listened to our concerns and opinions I was very impressed.
Review from Google
Jun 18th, 2025
★★★★★
Dr. Mikhail is regarded as one of the finest GI Oncologists in Ohio. He was recommended VERY highly by my surgeon. Dr. Mikhail is so knowledgeable and on top for the most up to date treatments and managing my side effects well. He listens EXTREMELY well, too.
Review from Google
Jun 10th, 2025
★★★★★
Dr. Mikhail was very detailed with his knowledge & explained everything very well. He made me feel comfortable with something that I was previously dreading.
Review from Google
Jun 5th, 2025
★★★★★
Dr. Mikhail is a wonderful doctor. He has a calm, reassuring manner. I have benefited from his professional medical expertise for the past six years .
Review from Google